What might long-term oxygen therapy lead to in patients?

Long-term oxygen therapy can indeed lead to hyperoxia, which is a condition characterized by an excess of oxygen in the tissues. While oxygen is vital for cellular metabolism, excessive levels can result in toxic effects, particularly in the lungs. The risk of hyperoxia becomes a concern when patients are exposed to supplemental oxygen over extended periods, especially at higher concentrations. This can lead to oxidative stress, inflammation, and damage to lung tissues.

In the context of oxygen therapy, it is essential to monitor oxygen levels and adjust therapy accordingly to avoid the dangers associated with hyperoxia while still ensuring adequate oxygenation for the patient. Understanding the balance of oxygen administration is crucial in the management of patients requiring long-term therapy.